Genotoxicity assessment in oncology nurses handling anti-neoplastic drugs
نویسندگان
چکیده
منابع مشابه
Genotoxicity assessment in oncology nurses handling anti-neoplastic drugs.
Many anti-neoplastic drugs are used globally during chemotherapy in the treatment of cancer. However, occupational exposure to anti-cancer drugs can represent a potential health risk to humans. Investigations on the genotoxicity of these drugs are inconsistent. Further, information on the genotoxic potential of anti-neoplastic drugs in medical personnel from India is not available. Hence, the a...
متن کاملOccupational risk assessment of genotoxicity and oxidative stress in workers handling anti-neoplastic drugs during a working week.
Twenty pharmacists and nurses handling anti-neoplastic drugs in a hospital were monitored during a working week, from Monday to Friday, in the morning (only on Monday) and afternoon (all days). Genotoxicity was analysed by the comet assay and the micronucleus (MN) test, while oxidative stress was analysed in serum by thiobarbituric acid reactive substances (TBARS) and by measurements of the ant...
متن کاملknowledge, attitude, and performance of oncology nurses handling antineoplastic drugs in hospitals of urmia university, iran
original article introduction: antineoplastic drugs (ands) for the treatment of cancers could result in occupational exposure of nurses and consequent side effects. this study aimed to evaluate knowledge, attitude, and performance of oncology nurses and to survey nurses’ chemotherapy workload and the experienced side effects. method: a cross-sectional study was conducted at four hospitals of ...
متن کاملhematological changes in nurses handling antineoplastic drugs
a cross-sectional study to determine whether occupational exposure to antineoplastic drugs can cause hematologic changes was performed. blood samples were collected from a group of 24 hematology/oncology nurses who were exposed to antineoplastic drugs during a mean preiod of 5.5 years (standard error =1.1). the control group, matched by sex, and age, consisted of 18 nurses, worked on other sect...
متن کاملDetermination of Urinary Cyclophosphamide in Oncology Nurses Handling Antineoplastic Drugs by Gas Chromatography-Mass Spectrometry
125 Determination of Urinary Cyclophosphamide in Oncology Nurses Handling Antineoplastic Drugs by Gas Chromatography-Mass Spectrometry Summary : The aim of the study was to detect exposure to antineoplastic drugs, using cyclophosphamide (CP) as the model compound, in nurses who worked in oncology departments of hospitals. Chemotherapy with antineoplastic agents is often used in the treatment of...
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ژورنال
عنوان ژورنال: Mutagenesis
سال: 2007
ISSN: 0267-8357,1464-3804
DOI: 10.1093/mutage/gem032